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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and exercise.
Using two separate drugs to shed weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you ought to err along the side of caution and let the FDA do its job and demand some investigation be done so the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on their own medications.
Researchers found out that participants using this drug for the year, lost excess weight within four weeks and have kept the extra weight off during the entire 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, which can make them far better and safer.
Combo-pilling may be the newest fad or in addition to this the newest to come under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular may be the fact that by right now there aren't any long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA.
Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise blood pressure level and pulse rate, and mustn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure levels, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.
Most of the combinations which are used to enhance weight loss involve an amphetamine and an antidepressant. Phentermine and Prozac are a popular combination that were around for a while, although it has been around nobody wants to truly combine both the and try to get FDA approval to market it as a weight-loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies do not want to be involved in combining medications and selling them something should be wrong with all the combination. In fairness there's one weight reduction combination pill which is in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and drug addiction, with the antidepressant bupropion (Wellbutrin, Zyban) it's been given the just do it to move forward by an FDA advisory committee, but since yet has not been approved.